Coupling Pulsed Laser Desorption and Ionization Loss Stimulated Raman Spectroscopy

by Tuval Bendosa

at Quantum optics seminar

Thu, 21 Jun 2018, 15:30
Physics building (#54) room 207

Abstract

Studies on biological and biological relevant molecules are most important for deepening our molecular level understanding on these systems A new strategy that emerged for revealing intrinsic properties of isolated biomolecules includes laser spectroscopies that probe electronic vibrational and rotational transition of neurotransmitters deoxyribonucleic acid DNA bases and others Our group developed and employs a stimulated Raman ultraviolet UV double resonance method namely ionization loss stimulated Raman spectroscopy ILSRS for measurement of molecular vibrational frequencies and for monitoring conformer specific spectra in extended spectral ranges This method was used up to now for monitoring the spectra of gas phase molecules obtained from volatile and thermally vaporized neurotransmitters but could not be applied to non volatile molecules This obstacle could be surpassed by employing laser desorption of solid samples mixed with graphite to yield gas phase molecules so that following their jet cooling wavelength and mass selective detection of molecules desorbed from a surface without fragmentation could be achieved Here we focused on designing building and characterizing a new laser desorption molecular beam source tailored for coupling it to the TOFMS and for use in spectroscopic measurements It is anticipated that this newly built system will provide the possibility to detect mass selectively molecules desorbed from a surface and its combination with ILSRS will open a new and broad spectroscopic window to nucleobases in the gas phase

Created on 17-06-2018 by Bar Lev, Yevgeny (ybarlev)
Updaded on 17-06-2018 by Bar Lev, Yevgeny (ybarlev)