Modelling the morphologies of the Endoplasmic Reticulum

by Tom Shemesh

at Physics Colloquium

Thu, 03 Apr 2014, 15:30
Physics building (#54) room 207

Abstract

The peripheral endoplasmic reticulum ER is an extensive membrane structure that is found in eukaryote cells and is the site for many key biological functions: folding and maturation of secretion bound proteins lipid synthesis and Ca2 regulation The ER forms a continuous membrane system with a common internal space and consists of domains that can adopt different morphologies such as: tubules flat sheets sheets with holes fenestrations and stacked sheets We show that the generation of tubules and sheets can be explained by curvature stabilizing proteins such as

Created on 30-03-2014 by Bar Lev, Yevgeny (ybarlev)
Updaded on 30-03-2014 by Bar Lev, Yevgeny (ybarlev)